Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.688


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXJ1chr17_-_741373700.647.2e-03Click!
FOXF1chr16_+_86544104-0.292.8e-01Click!
FOXF2chr6_+_1390068-0.273.1e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_161193190 8.796 APOA2
apolipoprotein A-II
chr1_-_161193375 8.260 NM_001643
APOA2
apolipoprotein A-II
chr4_+_74269971 5.459 NM_000477
ALB
albumin
chr22_+_21128378 5.001 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr4_+_155484131 4.419 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr4_+_74270832 4.246 ALB
albumin
chr4_+_100495972 4.074 MTTP
microsomal triglyceride transfer protein
chr17_-_7082559 4.068 ASGR1
asialoglycoprotein receptor 1
chr17_-_7082654 3.359 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr14_-_94789641 3.255 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr7_-_87342569 3.204 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr1_-_169555624 3.089 F5
coagulation factor V (proaccelerin, labile factor)
chr9_-_116840545 3.026 AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_207277577 3.022 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr6_-_41715078 2.999 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr12_-_63328857 2.983 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr7_+_134832765 2.978 NM_018295
TMEM140
transmembrane protein 140
chr10_-_52645384 2.904 A1CF
APOBEC1 complementation factor
chr14_+_95078713 2.866 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr17_+_72427535 2.856 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chrX_-_131573638 2.732 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr10_-_52645430 2.553 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr9_-_116840460 2.511 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_-_69886112 2.316 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr1_-_169555710 2.282 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr20_-_45976626 2.195 ZMYND8
zinc finger, MYND-type containing 8
chr9_-_116840551 2.188 AMBP
alpha-1-microglobulin/bikunin precursor
chr17_-_26697293 2.170 VTN
vitronectin
chr6_+_31895201 2.104 NM_000063
NM_001145903
C2

complement component 2

chr19_+_18496966 2.102 NM_004864
GDF15
growth differentiation factor 15
chr12_-_53343607 2.056 KRT8
keratin 8
chr1_-_24469571 2.053 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr11_-_115375065 2.028 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr4_+_71062241 2.013 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr20_-_22566092 1.993 NM_153675
FOXA2
forkhead box A2
chr17_-_26697310 1.978 VTN
vitronectin
chr13_-_46756326 1.974 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_26697224 1.972 VTN
vitronectin
chr11_+_22688156 1.962 NM_001143830
GAS2
growth arrest-specific 2
chr13_-_41240607 1.953 NM_002015
FOXO1
forkhead box O1
chr4_-_155511838 1.937 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr11_-_116708334 1.927 NM_000039
APOA1
apolipoprotein A-I
chr1_+_227127993 1.926 ADCK3
aarF domain containing kinase 3
chr19_-_48389514 1.916 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr2_+_33661392 1.916 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_227127959 1.902 ADCK3
aarF domain containing kinase 3
chr10_+_5005453 1.893 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_-_5045967 1.864 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr10_+_5005601 1.844 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr13_-_46756295 1.841 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_11674241 1.833 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr2_-_165424993 1.825 GRB14
growth factor receptor-bound protein 14
chr12_-_71551564 1.754 TSPAN8
tetraspanin 8
chr3_-_12586962 1.749 NM_001195279
LOC100129480
uncharacterized LOC100129480
chr1_+_227127999 1.729 ADCK3
aarF domain containing kinase 3
chr12_-_96390002 1.672 NM_002108
HAL
histidine ammonia-lyase
chr17_-_26697358 1.646 NM_000638
VTN
vitronectin
chr2_+_219646448 1.631 NM_000784
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr8_-_80993009 1.612 NM_001025252
TPD52
tumor protein D52
chr1_-_24194760 1.575 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr6_-_25930838 1.553 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr2_+_75059781 1.553 NM_000189
HK2
hexokinase 2
chr3_+_98451537 1.544 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr17_-_7017971 1.534 ASGR2
asialoglycoprotein receptor 2
chr10_+_102732285 1.522 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr10_+_7745341 1.522 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_220042948 1.493 FAM134A
family with sequence similarity 134, member A
chr9_-_116840604 1.437 AMBP
alpha-1-microglobulin/bikunin precursor
chr7_+_134233848 1.415 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr2_-_44065888 1.370 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr10_+_5005685 1.363 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr4_+_39063851 1.355 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr12_-_31479038 1.343 FAM60A
family with sequence similarity 60, member A
chr20_-_62582478 1.329 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr5_-_98262217 1.322 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr2_+_86947387 1.319 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr14_-_21493122 1.303 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr2_+_143635225 1.287 KYNU
kynureninase
chr2_+_86947429 1.248 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_-_122159140 1.230 CLASP1
cytoplasmic linker associated protein 1
chr10_+_5136589 1.229 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr15_+_74907334 1.217 NM_001130028
CLK3
CDC-like kinase 3
chr10_+_5136556 1.216 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_+_192544856 1.208 NM_002922
RGS1
regulator of G-protein signaling 1
chr12_-_9268522 1.199 NM_000014
A2M
alpha-2-macroglobulin
chr2_+_143635194 1.194 NM_001032998
NM_001199241
NM_003937
KYNU


kynureninase


chr2_+_86947570 1.192 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr10_+_7745325 1.190 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr13_-_46756291 1.189 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_26400503 1.187 NM_001199837
SNX10
sorting nexin 10
chr9_+_79968344 1.173 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr17_+_67410825 1.155 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr7_+_45933096 1.133


chr7_+_1127722 1.128 NM_001098201
GPER
G protein-coupled estrogen receptor 1
chr15_-_70994608 1.123 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr20_-_44993000 1.121 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr12_-_31479120 1.106 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr10_-_45474210 1.104 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr1_-_230850335 1.100 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_57431620 1.094 NM_000066
C8B
complement component 8, beta polypeptide
chr8_-_28243941 1.089 NM_018660
ZNF395
zinc finger protein 395
chr2_-_21266809 1.073 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_+_68424444 1.067 NM_012108
STAP1
signal transducing adaptor family member 1
chr10_+_5136613 1.061 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr12_+_8332789 1.059 FAM66C
family with sequence similarity 66, member C
chr12_-_31479084 1.039 FAM60A
family with sequence similarity 60, member A
chr10_+_7745229 1.036 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_-_33360641 1.020 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr2_-_128615691 1.006 POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr7_-_140624280 1.002 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr3_-_183273407 1.002 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chrX_+_46940235 1.000 RGN
regucalcin (senescence marker protein-30)
chr10_+_7745354 0.996 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr8_-_134309448 0.995 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr10_+_7745284 0.984 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_128176019 0.961 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr14_+_100563817 0.959 EVL
Enah/Vasp-like
chrX_-_48693934 0.952 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_-_25268057 0.950 NM_022150
NPVF
neuropeptide VF precursor
chr15_-_65412175 0.947 PDCD7
programmed cell death 7
chr11_-_5526833 0.921 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chr12_-_71551778 0.915 NM_004616
TSPAN8
tetraspanin 8
chr1_+_220960038 0.906 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr1_-_247054277 0.905 AHCTF1
AT hook containing transcription factor 1
chr1_-_231560789 0.895 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr6_-_76203256 0.895 NM_015687
FILIP1
filamin A interacting protein 1
chr11_-_65150107 0.881 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr1_+_227127937 0.861 NM_020247
ADCK3
aarF domain containing kinase 3
chr9_-_116840673 0.855 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_74301932 0.855 NM_001134
AFP
alpha-fetoprotein
chr14_-_21566728 0.848 NM_016423
ZNF219
zinc finger protein 219
chr18_-_52626636 0.836 NM_025214
CCDC68
coiled-coil domain containing 68
chr14_-_20797532 0.826 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chrX_-_15288172 0.820 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr7_+_112063131 0.799 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr10_-_54531394 0.783 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr5_+_154092461 0.779 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr6_-_43027114 0.774 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr10_-_72648540 0.766 NM_000281
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr4_-_89978117 0.765 NM_014883
FAM13A
family with sequence similarity 13, member A
chr5_-_42811959 0.763 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr2_-_27579277 0.761 GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr1_+_198608244 0.757 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_242127923 0.754 NM_001001666
NM_001001891
ANO7

anoctamin 7

chr1_+_236686738 0.753 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr5_-_131132642 0.738 FNIP1
folliculin interacting protein 1
chr21_+_34602304 0.735 IFNAR2
interferon (alpha, beta and omega) receptor 2
chr6_+_30130982 0.733 NM_033229
TRIM15
tripartite motif containing 15
chr6_-_2176224 0.733 NM_001253846
GMDS
GDP-mannose 4,6-dehydratase
chr11_-_46615497 0.731 AMBRA1
autophagy/beclin-1 regulator 1
chr18_+_60382617 0.731 NM_194449
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr1_-_47695442 0.730 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr3_-_58522873 0.729 NM_003500
ACOX2
acyl-CoA oxidase 2, branched chain
chr14_+_39736529 0.722 CTAGE5
CTAGE family, member 5
chr22_+_37309618 0.720 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr17_-_7018049 0.716 NM_001181
NM_001201352
NM_080912
NM_080913
ASGR2



asialoglycoprotein receptor 2



chr17_-_29641068 0.711 EVI2B
ecotropic viral integration site 2B
chr8_-_110655418 0.710 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr12_-_103311380 0.706 NM_000277
PAH
phenylalanine hydroxylase
chrX_+_70315637 0.701 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr6_-_150057659 0.700 NUP43
nucleoporin 43kDa
chr2_-_65593866 0.684 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr10_-_118680978 0.681 KIAA1598
KIAA1598
chr14_+_102276279 0.668 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_151770611 0.666 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr5_+_70944968 0.653 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr13_+_36050885 0.649 NM_001204197
NBEA
neurobeachin
chr8_+_107738239 0.647 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_11623829 0.644 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr12_-_9913415 0.643 NM_001781
CD69
CD69 molecule
chr17_-_29641087 0.633 EVI2B
ecotropic viral integration site 2B
chr12_-_49504337 0.632 LMBR1L
limb region 1 homolog (mouse)-like
chr18_-_74844710 0.625 MBP
myelin basic protein
chr1_+_50571963 0.624 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr21_+_34602205 0.620 NM_000874
NM_207584
NM_207585
IFNAR2


interferon (alpha, beta and omega) receptor 2


chr3_-_185826748 0.619 NM_004454
ETV5
ets variant 5
chr10_+_111985628 0.616 NM_005962
MXI1
MAX interactor 1
chr8_+_66933790 0.614 NM_033105
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr13_+_41885340 0.612 NM_001110798
NM_018527
NM_024561
NAA16


N(alpha)-acetyltransferase 16, NatA auxiliary subunit


chr20_+_48552928 0.610 RNF114
ring finger protein 114
chr14_+_32798478 0.603 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr9_+_134000939 0.602 NM_005085
NUP214
nucleoporin 214kDa
chr17_-_76124791 0.602 NM_001127198
TMC6
transmembrane channel-like 6
chr13_-_48987652 0.601 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr2_+_143886969 0.593 ARHGAP15
Rho GTPase activating protein 15
chr12_-_9268475 0.589 A2M
alpha-2-macroglobulin
chr2_-_88926863 0.588 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr1_+_28764660 0.586 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr1_+_198608216 0.585 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_9268513 0.582 A2M
alpha-2-macroglobulin
chr14_-_74551073 0.579 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr6_+_17600504 0.577 NM_016255
FAM8A1
family with sequence similarity 8, member A1
chr1_-_151414641 0.568 NM_207171
POGZ
pogo transposable element with ZNF domain
chr19_-_39826676 0.566 NM_004877
GMFG
glia maturation factor, gamma
chr16_-_11375094 0.561 NM_002761
PRM1
protamine 1
chr4_+_187187342 0.561 F11
coagulation factor XI
chr20_+_48552935 0.561 RNF114
ring finger protein 114
chr7_+_44646180 0.558 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr11_-_102826433 0.553 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr7_-_87230170 0.548 ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
10.69 4.40e-04 GO:0051346 negative regulation of hydrolase activity
16.74 8.28e-04 GO:0010951 negative regulation of endopeptidase activity
16.17 1.02e-03 GO:0055088 lipid homeostasis
93.70 1.47e-03 GO:0030300 regulation of intestinal cholesterol absorption
20.56 2.34e-03 GO:0030301 cholesterol transport
20.03 2.67e-03 GO:0015918 sterol transport
6.74 4.10e-03 GO:0008202 steroid metabolic process
12.67 4.31e-03 GO:0002576 platelet degranulation
18.17 4.38e-03 GO:0042632 cholesterol homeostasis
18.17 4.38e-03 GO:0055092 sterol homeostasis
29.75 5.00e-03 GO:0034367 macromolecular complex remodeling
29.75 5.00e-03 GO:0034368 protein-lipid complex remodeling
29.75 5.00e-03 GO:0034369 plasma lipoprotein particle remodeling
66.93 5.08e-03 GO:0010873 positive regulation of cholesterol esterification
58.57 8.09e-03 GO:0010872 regulation of cholesterol esterification
11.03 9.64e-03 GO:0010466 negative regulation of peptidase activity
25.00 1.04e-02 GO:0071825 protein-lipid complex subunit organization
25.00 1.04e-02 GO:0071827 plasma lipoprotein particle organization
10.78 1.10e-02 GO:0007586 digestion
46.86 1.72e-02 GO:0034374 low-density lipoprotein particle remodeling
39.05 3.12e-02 GO:0034377 plasma lipoprotein particle assembly
39.05 3.12e-02 GO:0044058 regulation of digestive system process
39.05 3.12e-02 GO:0065005 protein-lipid complex assembly
3.17 3.50e-02 GO:0006629 lipid metabolic process
18.38 3.64e-02 GO:0097006 regulation of plasma lipoprotein particle levels
17.86 4.09e-02 GO:0008206 bile acid metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
18.03 1.03e-04 GO:0031983 vesicle lumen
16.62 1.33e-03 GO:0031093 platelet alpha granule lumen
16.28 1.47e-03 GO:0034774 secretory granule lumen
15.63 1.80e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.53 1.90e-03 GO:0005615 extracellular space
13.95 3.16e-03 GO:0031091 platelet alpha granule
2.42 6.48e-03 GO:0005576 extracellular region
3.00 7.25e-03 GO:0044421 extracellular region part
6.08 1.68e-02 GO:0030141 stored secretory granule
26.04 2.18e-02 GO:0034361 very-low-density lipoprotein particle
26.04 2.18e-02 GO:0034385 triglyceride-rich lipoprotein particle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
17.64 1.76e-05 GO:0004867 serine-type endopeptidase inhibitor activity
156.16 3.62e-05 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
62.47 4.53e-05 GO:0017127 cholesterol transporter activity
52.06 1.06e-04 GO:0015248 sterol transporter activity
117.12 1.44e-04 GO:0047023 androsterone dehydrogenase activity
9.69 1.07e-03 GO:0004866 endopeptidase inhibitor activity
9.52 1.20e-03 GO:0030414 peptidase inhibitor activity
9.28 1.42e-03 GO:0061135 endopeptidase regulator activity
13.71 4.34e-03 GO:0005319 lipid transporter activity
7.66 4.95e-03 GO:0061134 peptidase regulator activity
156.16 5.82e-03 GO:0047026 androsterone dehydrogenase (A-specific) activity
156.16 5.82e-03 GO:0047718 indanol dehydrogenase activity
12.81 6.05e-03 GO:0005496 steroid binding
5.64 1.19e-02 GO:0004857 enzyme inhibitor activity
33.47 1.25e-02 GO:0070325 lipoprotein particle receptor binding
4.33 1.39e-02 GO:0008289 lipid binding
104.11 1.74e-02 GO:0004873 asialoglycoprotein receptor activity
104.11 1.74e-02 GO:0034190 apolipoprotein receptor binding
104.11 1.74e-02 GO:0070653 high-density lipoprotein particle receptor binding
22.32 4.43e-02 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor